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Well the clan itself is a bloodline, but so far they have shown no Kekkei Genkai. However, they have been known to have extremely large amounts of stamina and chakra, and can live longer than most people, i.e. Mito Uzumaki, so they make great Jinchuriki hosts, especially for the Kyuubi. The Uzumaki are distant blood relatives of the Senju. 

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